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Progesterone injection, a progestin, is a sterile solution of progesterone in a suitable vegetable oil available for intramuscular use. Progesterone occurs as a white or creamy white, crystalline powder. It is odorless and is stable in air. Practically insoluble in water, it is soluble in alcohol, Thrombophlebitis Assays, acetone, and dioxane and sparingly soluble in vegetable oils. Before using progesterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
This product may contain inactive ingredients such as sesame Thrombophlebitis Assayswhich can cause allergic reactions or other problems, Thrombophlebitis Assays. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: Before using this medication, tell your doctor or pharmacist your medical history, especially of: This drug is indicated in amenorrhea and abnormal uterine bleeding due to hormonal imbalance in the absence Thrombophlebitis Assays organic pathologysuch as submucous fibroids or uterine cancer.
Progesterone is administered by intramuscular injection. It differs from other commonly used steroids in that it is irritating at the place of injection.
Five to 10 mg are given for six to eight consecutive days. If there has been sufficient ovarian activity to produce a proliferative endometriumone can expect withdrawal bleeding forty-eight to seventy-two hours after the last injection.
This may be followed by spontaneous normal cycles. Five to 10 mg are given daily for six doses. Bleeding may be expected to cease within six days. When estrogen is given as well, the administration of progesterone is begun after two weeks of estrogen therapy.
If menstrual flow begins during the course of injections of progesterone, they are discontinued. Parenteral drug Thrombophlebitis Assays should be inspected visually for particulate matter and discoloration prior to administration whenever the solution and container permit, Thrombophlebitis Assays. A statistically significant association has been demonstrated between use of estrogen- progestin combination drugs and pulmonary embolism and cerebral thrombosis and embolism.
For this reason patients on progestin therapy should be carefully observed. There is also evidence suggestive of an association with neuro-ocular lesions, e, Thrombophlebitis Assays.
The following adverse reactions have been observed in patients receiving estrogen- progestin combination drugs: Rise in blood pressure in susceptible individual, premenstrual syndromechanges in libido, changes in appetite, cystitis-like syndrome, headache, Thrombophlebitis Assays, nervousness, fatigue, backache, hirsutism, loss of scalp hair, erythema multiformeerythema nodosumThrombophlebitis Assays, hemorrhagic eruption, itching, and dizziness.
The following laboratory results may be altered by the use of estrogen-progestin combination drugs: The physician Thrombophlebitis Assays be alert to the earliest manifestations of thrombotic disorders thrombophlebitiscerebrovascular disorders, pulmonary embolismand retinal thrombosis.
Should any of these occur or be suspected, the drug should be discontinued immediately. Medication should be discontinued pending examination if there is a sudden partial or complete loss of vision, or if there is a sudden onset of proptosis, diplopia or migraine. If examination reveals papilledema or Thrombophlebitis Assays vascular lesions, medication should be withdrawn, Thrombophlebitis Assays. The pretreatment physical examination should include special reference to breast and pelvic organs, Thrombophlebitis Assays, as well as a Papanicolaou smear.
Because progestational drugs may cause some degree of fluid retention, Thrombophlebitis Assays, conditions which might be influenced by this condition, Thrombophlebitis Assays, such as epilepsymigraine, asthmaThrombophlebitis Assays, cardiac, or renal dysfunction, require careful observation. In cases of breakthrough bleeding, as in all Thrombophlebitis Assays of irregular abstrakt Krampfadern Krankheit bei Sportlern per vaginumnonfunctional causes should be borne in mind, and adequate diagnostic measures undertaken.
Patients who have a history of psychic depression should be carefully observed and the drug discontinued if Thrombophlebitis Assays depression recurs to a serious degree. The age of the patient constitutes no absolute limiting factor although treatment with welche Medikamente für Krampfadern in den Beinen may mask the onset of the climacteric.
There are possible risks which may be associated with Thrombophlebitis Assays use of progestin treatment, including adverse effects on carbohydrate and lipid metabolism. The dosage used may be important in minimizing these adverse effects.
A decrease in glucose tolerance has been observed in a small percentage of patients Thrombophlebitis Assays estrogen-progestin combination treatment. The mechanism of this decrease is obscure. For this reason, diabetic patients should be carefully observed while receiving such therapy. Long-term intramuscular administration of Medroxyprogesterone acetate MPA has been shown to produce mammary tumors in beagle dogs.
There is no evidence of a carcinogenic effect associated with the oral administration of MPA to rats Thrombophlebitis Assays mice. Medroxyprogesterone acetate was not Schwarzkümmel Krampfadern an den Beinen in a battery of in vitro or in vivo genetic toxicity assays.
Progesterone at high doses is an antifertility drug and high doses would be expected to impair fertility until the cessation of treatment. The safety and effectiveness in geriatric patients over age 65 have not been established. Safety and effectiveness in pediatric patients have not been established, Thrombophlebitis Assays. Detectable amounts of drug have been identified in the milk of mothers receiving progestational drugs. The effect of this on the nursing infant has not been determined.
Thrombophlebitis Assays proliferative endometrium into secretory endometrium. Inhibits at the usual dose range the secretion of pituitary gonadotropins, which in turn prevents follicular maturation and ovulation. Progesterone is metabolized primarily in the liver by reduction to pregnanediol, pregnanetriol and pregnanolone.
Subsequent conjugation results in the Thrombophlebitis Assays of glucuronide and sulfate metabolites. The glucuronide and sulfate conjugates of pregnanediol and pregnanolone are excreted in the urine and bile. Progesterone metabolites which are excreted in the bile may undergo enterohepatic recycling or may be excreted in the feces. The pharmacokinetic data was determined in a small number of patients, limiting the precision in which population values may Thrombophlebitis Assays estimated.
The safety and effectiveness in patients with renal insufficiency have not been established. The safety and effectiveness in patients with hepatic insufficiency have not been established. Ketoconazole is a known inhibitor of cytochrome P 3A4 and these data suggest that ketoconazole or other known inhibitors of this enzyme may increase the bioavailability of progesterone. The clinical relevance of the in vitro findings is unknown.
Please read this information carefully before you start to Thrombophlebitis Assays Progesterone Injection and each time your prescription is renewed, in case anything has changed. This leaflet does not take the place of discussions with your doctor.
If you still have any questions, ask your doctor or health-care provider, Thrombophlebitis Assays. Progesterone Injection Thrombophlebitis Assays a sterile injectable solution containing the natural female hormone called progesterone.
Progesterone Injection is indicated for the treatment of amenorrhea and abnormal uterine bleeding due to progesterone deficiency, Thrombophlebitis Assays. Understanding the role of Progesterone Injection in the treatment of your menstrual irregularities. Progesterone is one of the hormones essential for regular menstrual periods. If your doctor has determined your body does not produce enough progesterone on its own, Progesterone Injection may be prescribed to provide the Thrombophlebitis der unteren Extremitäten und Kompressen you need, Thrombophlebitis Assays.
When you do not produce enough progesterone, menstrual irregularities can occur. Progesterone Injection can provide you with the progesterone needed during a normal menstrual cycle.
The following side effects have been reported with Progesterone Injection. Consult your doctor if you experience Thrombophlebitis Assays of the side effects mentioned below, or other side Thrombophlebitis Assays. Be alert for unusual signs and symptoms.
If any of these warning Thrombophlebitis Assays or any other unusual symptoms happen while you are using Progesterone Injection, call your doctor immediately:. Progesterone Injection is intended for administration by injection into a muscle mass.
Following injection, the medication is absorbed into the bloodstream. Progesterone Injection will be administered to you by a health-care provider or your caregiver, Thrombophlebitis Assays. Your doctor will provide instructions regarding the dose and manner in which the medication should be injected.
Thrombophlebitis Assays your doctor's instructions closely. If you have any questions about product administration, ask your doctor or health-care provider. Vials are individually boxed. Do not use Progesterone Injection after the expiration date which is printed on the vial label. You are encouraged to report negative side effects of prescription drugs to the FDA. Progesterone Injection Generic Name: Last reviewed on RxList: For Consumers What are the precautions when taking progesterone injection Progesterone Injection?
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No fever of leukocytosis. CT or MRI may demonstrate intra- abdominal or retro-peritoneal source of infection. Pleural Space Infection AAST Grade Description Clincal Criteria Imaging Criteria Operative Criteria Pathologic Criteria I Retained hemothorax or pleural effusion with positive pleural fluid cultures Leukocytosis, fever, chest pain Pleural fluid consistent with blood or infected fluid no evidence of loculations Retained blood, blood clot, or other non-purulent fluid without lung trapping.
Culture of fluid positive for organisms II Purulent, free-flowing pleural effusion or hemothorax by imaging Respiratory failure, leukocytosis, fever, chest pain Pleural fluid consistent with blood or infected fluid; no evidence of loculation Retained blood, blood clot, with purulent areas OR completely purulent fluid. Acute inflammation involving epidermis, dermis, Thrombophlebitis Assays, sub-cutaneous fat, Thrombophlebitis Assays, and muscular fascia with cultures positive for organisms if available V Myonecrosis Myonecrosis Air deep to fascia; likely poor perfusion of muscle Extension of necrosis into muscle and deeper tissue Acute inflammation involving epidermis, dermis, sub- cutaneous fat, muscular fascia, adjacent tissue muscle, etc.
Thank you Your feedback has been sent. Imaging Criteria CT findings. Above, plus axillary fluid collections, extension of inflammatory changes well beyond the abscesses.
Acute inflammation of breast tissue and axillary lymph nodes with cultures positive for organisms, Thrombophlebitis Assays. Acute inflammation involving chest wall, fascia, muscles or ribs with or without necrosis and cultures positive for organisms, Thrombophlebitis Assays. Wall thickening; Thrombophlebitis Assays gallstones or sludge; pericholecystic fluid; non-visualization of gallbladder GB on hepatobiliary iminodiacetic acid HIDA scan.
Above, plus air in GB lumen, wall or in the biliary tree; focal mucosal defects without frank perforation. Above, plus pus in the GB lumen; necrosis of GB wall; intramural abscess; epithelial sloughing; no perforation.
Was ist die Folge trophischen Geschwüren peritonitis at multiple locations; abdominal distention with symptoms of bowel obstruction.
Perforation with disseminated contamination; erosion into adjacent structures chest, mediastinum, or abdomen. Abdominal wall defect present with abdominal contents lodged in defect; healthy appearing viscera. Local tenderness with non-reducible palpable hernia; may be associated with fever, tachycardia, or leukocytosis. Abdominal wall defect present Thrombophlebitis Assays abdominal contents lodged in defect; visibly inflamed but viable appearing viscera, Thrombophlebitis Assays.
Local tenderness with guarding, non-reducible palpable hernia with associated skin changes such as erythema. Hernia visible on CT with local stranding or inflammatory changes as well as contained fluid collection. Abdominal wall defect present with abdominal contents lodged in defect; gangrenous or perforated abdominal contents. Diffuse abdominal tenderness with guarding or rebound; non-reducible palpable hernia with associated skin changes such as erythema.
Hernia visible on CT with local stranding or inflammatory changes as well as diffuse fluid collections and inflammation. Abdominal wall defect present Thrombophlebitis Assays abdominal contents lodged in defect; gangrenous or perforated abdominal contents with diffuse contamination. Colon wall thickening with ascites or diffuse colonic dilation or diffuse coalescing pseudo-membranes.
Colonic thickening with localized or discontinuous transmural necrosis or ischemia with or without perforation or abscess. Intestinal distension with transition point; delayed contrast flow with some distal contrast; no evidence of bowel compromise.
Intestinal distension with transition point and no distal contrast flow; evidence of complete obstruction or impending bowel compromise. Wall thickening without mucosal or intestinal wall enhancement; intramural, Thrombophlebitis Assays, portal, or mesenteric pneumatosis. Extra-pancreatic extension of pancreatic necrosis involving adjacent organs, such as colonic necrosis. Drainage of fluid collections, complications related to abscesses, such as interloop abscesses causing bowel obstruction; hysterectomy, Thrombophlebitis Assays.
Perforation with associated collection that is not contained in a anatomic space or abscess but not disseminated. Perforation with disseminated air and fluid with loss of local anatomic planes at the site of perforation. Perforation with Thrombophlebitis Assays succus or purulent peritonitis and erosion into adjacent structures. Fever; perineal pain; diffuse swelling; pain with defecation; palpable fluctuant area on digital examination. Fever; may present with sepsis Thrombophlebitis Assays perineal discomfort; may have no localized clinical signs, Thrombophlebitis Assays.
Systemic signs of sepsis, perineal pain and swelling, cellulitis, crepitus, necrotic skin changes. X-ray or CT may demonstrate air in soft tissues. Pleural fluid consistent with blood or infected fluid with evidence of loculation; significantly decreased lung volumes. Retained blood, blood clot or other purulent fluid with diffuse Thrombophlebitis Assays inflammation and lung trapping. Thrombophlebitis Assays inflammation involving epidermis, dermis, and subcutaneous fat with cultures positive Thrombophlebitis Assays organisms if available.
Acute inflammation involving epidermis, dermis, sub-cutaneous fat, and muscular fascia with cultures positive for organisms if available. Acute inflammation Thrombophlebitis Assays epidermis, dermis, sub- cutaneous fat, muscular fascia, adjacent tissue muscle, etc. One or more of the Thrombophlebitis Assays Infection involving body cavity or deep space away from the site that was opened or manipulated during surgery, Thrombophlebitis Assays.
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Find resources about AIS. Indications Activase (alteplase) is indicated for the treatment of acute ischemic stroke. Exclude intracranial hemorrhage as the primary.
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Learn about Progesterone Injection (Progesterone Injection) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related.
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Progesterone official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.
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Blood Clots (Arterial & Venous) Overview. Blood clotting can be and is a very important natural process in which platelets, fibrin, blood cells and various components.